这是我经历过的最严重的痛苦。

It was the worst pain I'd ever experienced.

他痛苦地尖叫着，乞求麻醉。

He was screaming in/with pain and begging for anaesthetic.

他写了一篇关于露营的快乐和痛苦的文章。

He wrote an article on the pleasures and pains of camping.

有好的痛苦也有坏的痛苦。

There is good pain and bad pain.

自己既感到痛苦，也叫别人痛苦。

Both feel their pain, also called others pain.