To know the abzyme mechanism of soman hydrolysis, the structure-activity relationship of soman and abzyme was studied.
为了解其催化水解梭曼的机制,需对其进行构效关系研究。
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Objective : To explore novel strategy for soman antidote by chemical immunization.
文摘:目的: 探索用化学免疫方法防治梭曼中毒.
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Objective: To observe the changes of the activity of catecholamine neuron groups in the brain stem after acute soman intoxication.
目的:观察梭曼急性中毒后脑干儿茶酚胺神经元的活动变化。
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After subcutaneous administration , the concentration of C ( ± ) P ( - ) soman was determined by using DFP as internal standard.
用二异丙基氟磷酸酯作内标,测定小鼠皮下染毒后脑与膈肌中游离C ( ± ) P ( - ) 梭曼.
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Results: The synthesized antigen induced catalytic antibodies with high efficiency in catalyzing hydrolysis of nerve agent soman and a novel phospho -transesterification reaction was discovered.